Fungal Morphogenetic Pathways Are Required for the Hallmark Inflammatory Response during Candida albicans Vaginitis
نویسندگان
چکیده
منابع مشابه
Terconazole cream for non-Candida albicans fungal vaginitis: results of a retrospective analysis.
OBJECTIVE Although it is FDA-approved for use in vulvovaginal candidiasis caused by non-Candida albicans species, terconazole cream has not been been studied in patients with these infections. We sought to assess the clinical and mycological efficacy of terconazole cream in women with non-C. albicans vaginitis. METHODS The records of patients who had received a 7-day course of terconazole cre...
متن کاملMucosal Damage and Neutropenia Are Required for Candida albicans Dissemination
Candida albicans fungemia in cancer patients is thought to develop from initial gastrointestinal (GI) colonization with subsequent translocation into the bloodstream after administration of chemotherapy. It is unclear what components of the innate immune system are necessary for preventing C. albicans dissemination from the GI tract, but we have hypothesized that both neutropenia and GI mucosal...
متن کاملThe Ess1 prolyl isomerase is required for growth and morphogenetic switching in Candida albicans.
Prolyl-isomerases (PPIases) are found in all organisms and are important for the folding and activity of many proteins. Of the 13 PPIases in Saccharomyces cerevisiae only Ess1, a parvulin-class PPIase, is essential for growth. Ess1 is required to complete mitosis, and Ess1 and its mammalian homolog, Pin1, interact directly with RNA polymerase II. Here, we isolate the ESS1 gene from the pathogen...
متن کاملEvaluation of Candida Vaginitis Epidemic Caused by Candida Albicans in Women of Kazerun City
Introduction: Candida albicans is one of the most common causes of vaginitis and one of the most important reasons for women to visit health centers. The aim of this study was to determine Candida albicans infection and its related factors in women in Kazerun. Methods: This cross-sectional study was performed in 2017 on 150 samples extracted from the laboratory. Swab specimens were prepared fr...
متن کاملCandida vaginitis.
Candida vaginitis Other than the dermatophytic mycoses, Candida vaginitis is the most common fungal disease in the United Kingdom, described by Morton and Rashid (1977) as a near epidemic. Almost all the known facts about it are enumerative or descriptive and little is known of the factors affecting the pathogenesis, recrudescence, or recurrence of the mycosis. The facts do not disclose the psy...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2014
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.01417-13